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Pre-operative Assessment and Post-operative Outcomes of Elderly Women With Gynecologic Cancers
Primary Objective:
To determine whether the preoperative GA-GYN score will be associated with major post-operative complications in elderly patients undergoing open primary cytoreduction surgery.
Secondary Objectives:
To explore associations between individual variables of the preoperative geriatric assessment and major post-operative complications in patients undergoing open primary cytoreduction surgery.
To assess the association between the preoperative GA-GYN score and cytoreducibility defined by extent of residual disease in patients undergoing open primary cytoreduction surgery.
Exploratory Objectives:
To evaluate whether the preoperative GA-GYN scores obtained before and after neoadjuvant chemotherapy will be associated with major post-operative complications in elderly patients undergoing open interval cytoreduction surgery.
To describe reasons why surgeons at centers where open cytoreduction surgery is the standard of care choose to perform interval surgery vs. primary surgery, and to explore the association of the preoperative GA-GYN score with the decision to perform primary surgery or interval surgery or no surgery.
To collect the following specific information on how elderly women with suspected ovarian, fallopian tube, primary peritoneal carcinomas or advanced stage papillary serous uterine carcinoma are treated at centers that consider open cytoreduction surgery the standard of care: (1) the percentage of patients treated with primary open cytoreduction vs. interval open cytoreduction vs no surgery and (2) to ascertain the extent of cytoreduction.
To determine whether neoadjuvant chemotherapy will be associated with changes in the GA-GYN score to change by comparing the GA-GYN scores obtained before and after neoadjuvant chemotherapy.
To determine whether 30-day readmission rates after cytoreductive surgery correlate with the GA-GYN score.
Primary Objective:
To determine whether the preoperative GA-GYN score will be associated with major post-operative complications in elderly patients undergoing open primary cytoreduction surgery.
Secondary Objectives:
To explore associations between individual variables of the preoperative geriatric assessment and major post-operative complications in patients undergoing open primary cytoreduction surgery.
To assess the association between the preoperative GA-GYN score and cytoreducibility defined by extent of residual disease in patients undergoing open primary cytoreduction surgery.
Exploratory Objectives:
To evaluate whether the preoperative GA-GYN scores obtained before and after neoadjuvant chemotherapy will be associated with major post-operative complications in elderly patients undergoing open interval cytoreduction surgery.
To describe reasons why surgeons at centers where open cytoreduction surgery is the standard of care choose to perform interval surgery vs. primary surgery, and to explore the association of the preoperative GA-GYN score with the decision to perform primary surgery or interval surgery or no surgery.
To collect the following specific information on how elderly women with suspected ovarian, fallopian tube, primary peritoneal carcinomas or advanced stage papillary serous uterine carcinoma are treated at centers that consider open cytoreduction surgery the standard of care: (1) the percentage of patients treated with primary open cytoreduction vs. interval open cytoreduction vs no surgery and (2) to ascertain the extent of cytoreduction.
To determine whether neoadjuvant chemotherapy will be associated with changes in the GA-GYN score to change by comparing the GA-GYN scores obtained before and after neoadjuvant chemotherapy.
To determine whether 30-day readmission rates after cytoreductive surgery correlate with the GA-GYN score.
Recruitment Status
Past Studies